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TOPIC: Question about A-PVT

Question about A-PVT 1 year 10 months ago #4731

  • Wile-y G
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"This compound is the thiophenyl analogue of stimulant drug α-PVP."

My curiousity is eating me alive on this one. What is the chemical difference as far as in-vitro possibilities are concerned?
Any experiences out there in the forum? From what I can tell, it's somewhat newly vended, but I'm not 100% on that.

The chance at a first time report would be amazing!! Perhaps I'll bear this guinea-cross alone!! Hoo Rah!!
I'll keep in touch and be watching this thread w/ nano scale closeness!! lol.... :woohoo:
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Re: Question about A-PVT 1 year 10 months ago #4732

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Why the hell...

I understand A-PPT or A-PBT -maybe- but this one sounds horribly toxic.

MPA doesnt have a pyrrolidine ring, but these do, and MPA is already somewhat toxic and an MAOI.
"Your eyes may be open, but this does not mean that you can see."
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Re: Question about A-PVT 1 year 10 months ago #4733

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Toxic on a generalized scale? I know that ROA makes all the difference, but I'm wondering if one of these alphas are meant only for a specific route....

Can you give more info devourer?

I'm gladly worried now!! As such, I shall continue to learn and investigate.
Last Edit: 1 year 10 months ago by Wile-y G. Reason: To ask for more info
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Re: Question about A-PVT 1 year 10 months ago #4738

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The fact it would most likely be an MAOI is enough reason to avoid it.
an MAOI aPVP sounds so potentially deadly/neurotoxic.
"Your eyes may be open, but this does not mean that you can see."
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Re: Question about A-PVT 1 year 10 months ago #4743

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Devourer wrote:
Hi

MPA doesnt have a pyrrolidine ring, but these do, and MPA is already somewhat toxic and an MAOI.

I've done some googling about MPA being a MAOI. I could not find anything other than specalitions. Do you have a reference for that? I'm also curious about the toxicity, other than the typical vasoconstriction. I found a hypothesis[url] on bluelight, but how that would work is out beyond my comprehension.

Maybe this is better discussed in the mpa thread...
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Re: Question about A-PVT 1 year 10 months ago #4768

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The MAOI comes from the sulphur.

and Of course it is, Amphetamine is already an MAOI and a sulfur on an amphetamine anywhere usually enhances the MAOI effects.
this also makes sense MPA only gets good in high doses where the MAOI starts to make it more neurotoxic. (and therefore "enjoyable" to some)
"Your eyes may be open, but this does not mean that you can see."
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Re: Question about A-PVT 1 year 10 months ago #5806

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Devourer wrote:
The MAOI comes from the sulphur.

and Of course it is, Amphetamine is already an MAOI and a sulfur on an amphetamine anywhere usually enhances the MAOI effects.
this also makes sense MPA only gets good in high doses where the MAOI starts to make it more neurotoxic. (and therefore "enjoyable" to some)
Ampehtamine's activities come free releasing, reuptake , and agonist activities on at the respective sites for the three primary monoamines.

PMA is a compound whose MAOI activity is relevant, and that killed a number of people. That's dangerous. Tranylcypromine is a related compound which is an MAOI, and it has its recommended uses and so on.

MPA is not an MAOI as far as anything I've read in the literature could suggest nor anything I've seen people claim experientially.

I am significantly at a loss as to why you a-PVT is an MAOI.

Also, I've seen some a-PVT reports. They are far from stellar, but also far from disaster stories.
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Re: Question about A-PVT 1 year 9 months ago #5839

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I too have questions about it's mpa's maoi activity. If that is so, shouldn't it boost certain psychedelics, or make them explode? I Have read lots of reports before buying that stuff, but I don't remember anything other that interaction with mdai, which is likely attributable to bringing some dopamine in the mix rather that amplifying it sert-wise.

This discussion could really use some references to back things up.
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Re: Question about A-PVT 1 year 9 months ago #5843

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I'll make the first step....

here some research wrt maoi activity of a wide range of amphetamines.

What I get from it at first glance, is that the maoi activity varies greatly among the tested substances, with a couple of 'high rollers'. So saying that amphetamines are all maoi's is inaccurate. This makes the premise for "amphetamines are maoi, so therefore mpa should be" [1] quite shaky. Also the derivation [1] itself is not easy to prove. Best thing for us would be some scientists to cook up the results for mpa.
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Re: Question about A-PVT 1 year 9 months ago #5845

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Re-reading, I kinda misquoted you devourer. I rephrased as I incorrectly remembered.

Nevertheless, it's a nice article, I'll give it some more time later.
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